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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOC1
All Species:
43.33
Human Site:
Y759
Identified Species:
73.33
UniProt:
Q9NV70
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NV70
NP_001020095.1
894
101982
Y759
K
K
E
A
K
Q
K
Y
T
D
H
L
Q
S
Y
Chimpanzee
Pan troglodytes
XP_001142521
886
101061
Y751
K
K
E
A
K
Q
K
Y
T
D
H
L
Q
S
Y
Rhesus Macaque
Macaca mulatta
XP_001087347
894
101935
Y759
K
K
D
A
K
Q
K
Y
T
D
H
L
Q
S
Y
Dog
Lupus familis
XP_532380
894
102004
Y759
K
K
E
A
K
Q
K
Y
T
D
H
L
Q
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3S6
894
101859
Y759
K
K
E
A
K
Q
K
Y
T
D
H
L
Q
S
Y
Rat
Rattus norvegicus
NP_001019941
681
76652
G567
L
S
R
P
Q
S
S
G
S
L
L
P
V
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506171
894
101975
Y759
K
R
E
A
K
Q
K
Y
T
D
H
L
Q
S
Y
Chicken
Gallus gallus
XP_001232097
895
102211
Y760
K
K
E
A
K
L
K
Y
T
E
H
L
Q
S
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_955891
892
101963
Y757
R
K
E
A
K
Q
K
Y
T
E
H
L
Q
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VVG4
889
102677
Y754
K
K
E
A
K
K
C
Y
N
D
A
L
K
A
Y
Honey Bee
Apis mellifera
XP_396967
859
98113
Y724
R
K
E
A
K
Q
K
Y
Q
D
A
L
R
A
Y
Nematode Worm
Caenorhab. elegans
Q20678
848
97279
K712
R
K
D
A
K
A
L
K
E
E
H
I
D
A
Y
Sea Urchin
Strong. purpuratus
XP_787291
869
100242
Y734
R
K
E
A
K
Q
Q
Y
Q
D
H
L
Q
S
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SX85
887
100046
A765
A
S
E
A
Y
E
Q
A
C
T
R
H
I
S
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
99.5
98.5
N.A.
97.1
70.9
N.A.
95
94
N.A.
84.6
N.A.
40.1
42
34.3
49.1
Protein Similarity:
100
98.2
100
98.8
N.A.
98.6
73.8
N.A.
97.1
96.6
N.A.
91.6
N.A.
62.4
62.5
54.5
68.7
P-Site Identity:
100
100
93.3
100
N.A.
100
6.6
N.A.
93.3
86.6
N.A.
86.6
N.A.
60
66.6
33.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
93.3
N.A.
100
N.A.
80
86.6
66.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
93
0
8
0
8
0
0
15
0
0
22
0
% A
% Cys:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
65
0
0
8
0
0
% D
% Glu:
0
0
79
0
0
8
0
0
8
22
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
72
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% I
% Lys:
58
79
0
0
86
8
65
8
0
0
0
0
8
0
0
% K
% Leu:
8
0
0
0
0
8
8
0
0
8
8
79
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
65
15
0
15
0
0
0
65
0
0
% Q
% Arg:
29
8
8
0
0
0
0
0
0
0
8
0
8
0
0
% R
% Ser:
0
15
0
0
0
8
8
0
8
0
0
0
0
79
8
% S
% Thr:
0
0
0
0
0
0
0
0
58
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
79
0
0
0
0
0
0
86
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _